The Wise Farm must probably be located at hex 154,38, with the field in front of it. A photo of the farm shows rail fences around the field, and to the north was an open pasture, bordered on the west and south by a stone wall. The main Confederate position was near the edge of the woods to the left of the Wise pasture, behind the stone fence on the east side of Ridge Road and along the Old Sharpsburg Road as it descends to the west..
Here is a screenshot from BG:Antietam. The Wise farm is just at the intersection of some roads at Fox's Gap. But I don't know how accurate this map is. Good sources are Priest's Before Antietam, and Luvaas & Nelson The Battle of Antietam.
MajGen Atle Jenssen
CO 2nd Division
XXth Corps
Army of the Cumberland
USA